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Vial filling machine

Technical Parameters

Bottle Specifications
Power Supply
380V
Power
3–5.5kW
Air Source
0.6–0.7MPa
1–50ml vials, bottle body diameter 16/22/28mm, mold change for specification changeover in 10min
Filling Volume
0.2–50ml adjustable, expandable to 100ml large bottle customization
Production Speed
Small semi-automatic: 30–60 bottles/minute; fully automatic turntable: 80–240 bottles/minute; high-speed linked line: 300–600 bottles/minute
Machine Body Material
Whole machine in 304/316L stainless steel, 316L for liquid contact parts, complying with GMP cleanroom standards

Complete Machine Workflow

Bottle Unscrambling and Infeed: the unscrambling disc automatically aligns the bottles, the star wheel indexes bottles with precise positioning, and photoelectric detection prevents filling when no bottle is present.
Precision Filling: the pump precisely dispenses material, with the filling needle inserted into the bottle to prevent splashing and liquid dripping.
Automatic Stopper Insertion: vibratory stopper unscrambling + vacuum stopper pickup, with free switching between half-stopping (for pre-lyophilization) and full-stopping (for finished product sealing).
Aluminum Cap Placement: a cap sorting machine arranges the aluminum-plastic caps and places them onto the bottle mouth.
Rolling Crimping: three-head/four-head roller crimping tightly seals the aluminum cap to the bottle mouth, meeting airtightness requirements.
Finished Bottle Discharge: discharge via conveyor, with automatic rejection of bottles with missing stoppers, missing caps, or defective filling.

Filling Pump Selection

Peristaltic Pump

Accuracy ±0.5%–±1%; applicable materials: vaccines, biological stock solutions, essences, easily oxidized liquids; advantages: the liquid contacts only the tubing, sterile, easy CIP cleaning, disposable tubing prevents cross-contamination.

Ceramic Plunger Pump

Accuracy ±0.3%–±0.8%; applicable materials: water-injection liquids, veterinary aqueous solutions, viscous essential oils; advantages: wear-resistant and durable, high-speed mass production, stable accuracy.

Servo Piston Pump

Accuracy within ±0.2%; applicable materials: high-viscosity pastes and liquids, suspensions, high-value medical aesthetic stock solutions; advantages: servo-metered, with suck-back cut-off, no dripping.

Applicable Filling Categories & Optional Upgrades

Applicable Filling Categories

Pharmaceutical: injection liquids, antibiotic water-injection solutions, vaccines, veterinary injection solutions, lyophilized liquids (filled and half-stopped before entering the lyophilizer).
Medical aesthetics / daily chemicals: hyaluronic acid stock solutions, lyophilized powder solvents, essence liquids, ampoule essential oils, repair stock solutions.
Health supplements: oral liquids, concentrated nutritional liquids, probiotic stock solutions, traditional Chinese medicine extracts.

Optional Upgrade Configurations

Nitrogen flushing before/after filling: isolates air, suitable for vitamin C, easily oxidized stock solutions, and essential oils.
CIP/SIP clean-in-place and sterilize-in-place: standard for sterile pharmaceutical workshops, high-temperature sterilization of the entire pipeline.
Inline weighing inspection: real-time calibration of filling volume, with automatic rejection of non-conforming items.
Powder filling module: one machine for two uses, switchable to powder injection filling (ginseng powder, cordyceps powder, lyophilized powder).

Packaging Samples

Dongguan Changsheng Packaging Machinery Co., Ltd.

Service Hotline: +86 137 1305 5565 +86 130 7138 5662 Address:

Room 305, Building 1, Jieshang Mansion, No. 63 Zhongli Road, Nancheng Subdistrict, Dongguan City